/* * This code is generated by BioUML FrameWork * for BIOMD0000000072.xml diagram at 2008.03.20 15:07:53 */ import biouml.plugins.simulation.ae.NewtonSolver; import biouml.plugins.simulation.java.JavaBaseModel; import ru.biosoft.math.MathRoutines; public class BIOMD0000000072 extends JavaBaseModel { /* * Write rules to calculate equation parameters */ /* * Write rules to calculate equation parameters excluding internal variables. */ public void __internalRateVarInitFunc_0(double time, double[] x) { rate_reaction_0 = cell*(reaction_0_k1*x[2]*x[3] - reaction_0_k2*x[6]); rate_reaction_1 = cell*reaction_1_v; rate_reaction_2 = cell*reaction_2_k1*x[3]; rate_reaction_3 = cell*reaction_3_k1*x[5]*x[1]; rate_reaction_4 = cell*reaction_4_k1*x[6]*x[0]; rate_reaction_5 = cell*reaction_5_k1*x[6]; rate_reaction_6 = cell*reaction_6_k1*x[4]; } public void Init() { initialValues = getInitialValues(); /* * Initialize variables */ cell = 1.0; // initial value of $cell reaction_0_k1 = 3.32E-18; // initial value of reaction_0_k1 reaction_0_k2 = 0.01; // initial value of reaction_0_k2 reaction_1_v = 4.0; // initial value of reaction_1_v reaction_2_k1 = 4.0E-4; // initial value of reaction_2_k1 reaction_3_k1 = 1.0; // initial value of reaction_3_k1 reaction_4_k1 = 1.0E-5; // initial value of reaction_4_k1 reaction_5_k1 = 0.0040; // initial value of reaction_5_k1 reaction_6_k1 = 0.11; // initial value of reaction_6_k1 } /* * Model variables initial values */ protected double rate_reaction_0; protected double rate_reaction_1; protected double rate_reaction_2; protected double rate_reaction_3; protected double rate_reaction_4; protected double rate_reaction_5; protected double rate_reaction_6; protected double cell; protected double reaction_0_k1; protected double reaction_0_k2; protected double reaction_1_v; protected double reaction_2_k1; protected double reaction_3_k1; protected double reaction_4_k1; protected double reaction_5_k1; protected double reaction_6_k1; public double[] extendResult(double time,double [] x) { this.time = time; double[] y = new double[7]; y[0] = x[0]; y[1] = x[1]; y[2] = x[2]; y[3] = x[3]; y[4] = x[4]; y[5] = x[5]; y[6] = x[6]; return y; } public double[] getInitialValues() { double [] x = new double[7]; this.time = 0.0; x[0] = 7000.0; // - $"cell.G" x[1] = 3000.0; // - $"cell.Gbg" x[2] = 6.02E17; // - $"cell.L" x[3] = 10000.0; // - $"cell.R" x[4] = 0.0; // - $cell.Ga x[5] = 3000.0; // - $cell.Gd x[6] = 0.0; // - $cell.RL __internalRateVarInitFunc_0(time, x); return x; } /* * code for algebraic rules calculations */ /* * end of code for algebraic rules calculations */ protected void calculateRates(double time, double[] x) { __internalRateVarInitFunc_0(time, x); } /* * calculate dy/dt for 'BIOMD0000000072.xml' model */ public void __internalDyDt_0(double time, double [] x, double[] result) { result[0] = +rate_reaction_3-rate_reaction_4; result[1] = -rate_reaction_3+rate_reaction_4; result[2] = -rate_reaction_0; result[3] = -rate_reaction_0+rate_reaction_1-rate_reaction_2; result[4] = +rate_reaction_4-rate_reaction_6; result[5] = -rate_reaction_3+rate_reaction_6; result[6] = +rate_reaction_0-rate_reaction_5; } protected double [] calculateResult(double time, double[] x) { double[] result = new double[7]; __internalDyDt_0(time, x, result); return result; } public double[] dy_dt(double time, double[] x) { this.time = time; calculateRates( time,x ); return calculateResult( time,x ); } } // class ...