/* * This code is generated by BioUML FrameWork * for BIOMD0000000077.xml diagram at 2008.03.20 15:07:58 */ import biouml.plugins.simulation.ae.NewtonSolver; import biouml.plugins.simulation.java.JavaBaseModel; import ru.biosoft.math.MathRoutines; public class BIOMD0000000077 extends JavaBaseModel { /* * Write rules to calculate equation parameters */ private void __internalVarInitFunc_0(double time, double[] x) { _compartment_0_species_8_ = 0.0010*parameter_1*x[6]*(0.3 + 0.3*parameter_2*time*Math.exp(1 - parameter_2*time))/(1 + 0.0010*parameter_1*x[6]); } /* * Write rules to calculate equation parameters excluding internal variables. */ public void __internalRateVarInitFunc_0(double time, double[] x) { rate_reaction_0 = compartment_0*(reaction_0_k1*x[0]*x[2] - reaction_0_k2*x[1]); rate_reaction_1 = compartment_0*(reaction_1_k1*Math.pow(x[1], 2.0) - reaction_1_k2*x[3]); rate_reaction_2 = compartment_0*(reaction_2_k1*x[3]*x[5] - reaction_2_k2*x[4]); rate_reaction_3 = compartment_0*reaction_3_k1*x[6]; rate_reaction_4 = compartment_0*reaction_4_k*x[4]; } public void Init() { initialValues = getInitialValues(); /* * Initialize variables */ compartment_0 = 1.0; // initial value of $compartment_0 parameter_1 = 2.0; // initial value of parameter_1 parameter_2 = 4.0; // initial value of parameter_2 reaction_0_k1 = 2.5; // initial value of reaction_0_k1 reaction_0_k2 = 5.0; // initial value of reaction_0_k2 reaction_1_k1 = 2500.0; // initial value of reaction_1_k1 reaction_1_k2 = 5.0; // initial value of reaction_1_k2 reaction_2_k1 = 4000.0; // initial value of reaction_2_k1 reaction_2_k2 = 200.0; // initial value of reaction_2_k2 reaction_3_k1 = 10.0; // initial value of reaction_3_k1 reaction_4_k = 2.0E7; // initial value of reaction_4_k } /* * Model variables initial values */ protected double _compartment_0_species_8_; protected double rate_reaction_0; protected double rate_reaction_1; protected double rate_reaction_2; protected double rate_reaction_3; protected double rate_reaction_4; protected double compartment_0; protected double parameter_1; protected double parameter_2; protected double reaction_0_k1; protected double reaction_0_k2; protected double reaction_1_k1; protected double reaction_1_k2; protected double reaction_2_k1; protected double reaction_2_k2; protected double reaction_3_k1; protected double reaction_4_k; protected double time; public double[] extendResult(double time,double [] x) { this.time = time; __internalVarInitFunc_0(time, x); double[] y = new double[8]; y[0] = x[0]; y[1] = x[1]; y[2] = x[2]; y[3] = x[3]; y[4] = x[4]; y[5] = x[5]; y[6] = x[6]; y[7] = _compartment_0_species_8_; return y; } public double[] getInitialValues() { double [] x = new double[7]; this.time = 0.0; x[0] = 1.0; // - $"compartment_0.species_0" x[1] = 0.0; // - $"compartment_0.species_1" x[2] = 0.01; // - $"compartment_0.species_2" x[3] = 0.0; // - $"compartment_0.species_3" x[4] = 0.0; // - $"compartment_0.species_4" x[5] = 0.1; // - $"compartment_0.species_5" x[6] = 0.0; // - $"compartment_0.species_6" __internalVarInitFunc_0(time, x); __internalRateVarInitFunc_0(time, x); return x; } /* * code for algebraic rules calculations */ /* * end of code for algebraic rules calculations */ protected void calculateRates(double time, double[] x) { __internalVarInitFunc_0(time, x); __internalRateVarInitFunc_0(time, x); } /* * calculate dy/dt for 'BIOMD0000000077.xml' model */ public void __internalDyDt_0(double time, double [] x, double[] result) { result[0] = -rate_reaction_0; result[1] = +rate_reaction_0-rate_reaction_1*2; result[2] = -rate_reaction_0; result[3] = +rate_reaction_1-rate_reaction_2; result[4] = +rate_reaction_2; result[5] = -rate_reaction_2; result[6] = -rate_reaction_3+rate_reaction_4; } protected double [] calculateResult(double time, double[] x) { double[] result = new double[7]; __internalDyDt_0(time, x, result); return result; } public double[] dy_dt(double time, double[] x) { this.time = time; calculateRates( time,x ); return calculateResult( time,x ); } public double[] checkEvent(double time, double[] x) { this.time = time; __internalVarInitFunc_0(time, x); __internalRateVarInitFunc_0(time, x); double [] flags = new double[1]; flags[0] = (time > 5) ? +1 : -1; //RemovalH return flags; } public void processEvent(int __internalVar12060040785150, double time, double[] x) { this.time = time; if ( __internalVar12060040785150 == 0) //RemovalH { x[0] = 0; } } } // class ...