Test: BIOMD0000000049.xml - Ok

test: BIOMD0000000049.xml
model: xml, reaction graph
plots: -
comparison: comparison of simulators

Reaction graph

Note: downloaded from http://www.ebi.ac.uk/compneur-srv/biomodels/models-main/publ/BIOMD0000000049.gif

Comparison with other simulators

Legend:

Text color indicates difference between values:
  -  no significant difference ( < 0.1%)
  -  small relative error ( > 0.1% and <50%)
  -  simulation results significantly differ ( >50%)

Variables: Grb2_SOS_pShc_dpEGFR_c_Cbl  pTrkA_endo  B_Raf_Rap1_GTP  B_Raf_Ras_GTP_MEK  FRS2_dpEGFR  Rap1_GDP  L_NGFR  dppERK  B_Raf  pSOS  Crk_C3G_pFRS2_pTrkA_endo  Grb2_SOS_pShc_pTrkA  Grb2_SOS_pShc_dpEGFR  c_Raf_Ras_GTP_pMEK_ERK  c_Raf_Ras_GTP_MEK  pFRS2  pShc_dpEGFR_c_Cbl  B_Raf_Ras_GTP  MEK_ERK  FRS2  Shc_dpEGFR  EGFR  pMEK  Crk  ppERK  Crk_C3G  ppMEK  Shc_dpEGFR_c_Cbl  c_Cbl  ppERK_MKP3  B_Raf_Ras_GTP_pMEK_ERK  FRS2_pTrkA_endo  pFRS2_dpEGFR  SOS_Grb2  pFRS2_pTrkA  NGFR  B_Raf_Rap1_GTP_MEK_ERK  Grb2_SOS_pShc_dpEGFR_c_Cbl_ubiq  Shc_pTrkA_endo  Crk_C3G_pFRS2_dpEGFR  pDok  pFRS2_dpEGFR_c_Cbl_ubiq  pMEK_ERK  B_Raf_Ras_GTP_pMEK  B_Raf_Rap1_GTP_pMEK_ERK  L_dpEGFR  Crk_C3G_pFRS2_dpEGFR_c_Cbl_ubiq  proteosome  FRS2_pTrkA  FRS2_dpEGFR_c_Cbl  c_Raf_Ras_GTP_MEK_ERK  pShc  dppERK_MKP3  Rap1_GTP  pShc_pTrkA  Ras_GTP  L_EGFR  Crk_C3G_pFRS2_dpEGFR_c_Cbl  Shc  pSOS_Grb2  RasGAP  c_Raf_Ras_GTP_pMEK  B_Raf_Rap1_GTP_MEK  ERK  Shc_pTrkA  pShc_dpEGFR  MEK  B_Raf_Rap1_GTP_pMEK  MKP3  c_Raf_Ras_GTP  Ras_GDP  pFRS2_dpEGFR_c_Cbl  dpEGFR_c_Cbl  pShc_dpEGFR_c_Cbl_ubiq  pTrkA  pFRS2_pTrkA_endo  dpEGFR_c_Cbl_ubiq  pDok_RasGAP  Crk_C3G_pFRS2_pTrkA  SOS  FRS2_dpEGFR_c_Cbl_ubiq  Grb2_SOS_pShc_pTrkA_endo  Dok  L_EGFR_dimer  ppMEK_ERK  Grb2  pShc_pTrkA_endo  C3G  B_Raf_Ras_GTP_MEK_ERK  Grb2_SOS_pShc  Shc_dpEGFR_c_Cbl_ubiq  c_Raf 
Simulators: BioUML  ByoDyn  Jarnac  MathSBML  Oscill8 Core  SBToolbox2  SBWOdeSolver  VCell  copasi  edu.kgi.roadRunner  jsim 
timesimulation Grb2_SOS_pShc_dpEGFR_c_Cbl pTrkA_endo B_Raf_Rap1_GTP B_Raf_Ras_GTP_MEK FRS2_dpEGFR Rap1_GDP L_NGFR dppERK B_Raf pSOS Crk_C3G_pFRS2_pTrkA_endo Grb2_SOS_pShc_pTrkA Grb2_SOS_pShc_dpEGFR c_Raf_Ras_GTP_pMEK_ERK c_Raf_Ras_GTP_MEK pFRS2 pShc_dpEGFR_c_Cbl B_Raf_Ras_GTP MEK_ERK FRS2 Shc_dpEGFR EGFR pMEK Crk ppERK Crk_C3G ppMEK Shc_dpEGFR_c_Cbl c_Cbl ppERK_MKP3 B_Raf_Ras_GTP_pMEK_ERK FRS2_pTrkA_endo pFRS2_dpEGFR SOS_Grb2 pFRS2_pTrkA NGFR B_Raf_Rap1_GTP_MEK_ERK Grb2_SOS_pShc_dpEGFR_c_Cbl_ubiq Shc_pTrkA_endo Crk_C3G_pFRS2_dpEGFR pDok pFRS2_dpEGFR_c_Cbl_ubiq pMEK_ERK B_Raf_Ras_GTP_pMEK B_Raf_Rap1_GTP_pMEK_ERK L_dpEGFR Crk_C3G_pFRS2_dpEGFR_c_Cbl_ubiq proteosome FRS2_pTrkA FRS2_dpEGFR_c_Cbl c_Raf_Ras_GTP_MEK_ERK pShc dppERK_MKP3 Rap1_GTP pShc_pTrkA Ras_GTP L_EGFR Crk_C3G_pFRS2_dpEGFR_c_Cbl Shc pSOS_Grb2 RasGAP c_Raf_Ras_GTP_pMEK B_Raf_Rap1_GTP_MEK ERK Shc_pTrkA pShc_dpEGFR MEK B_Raf_Rap1_GTP_pMEK MKP3 c_Raf_Ras_GTP Ras_GDP pFRS2_dpEGFR_c_Cbl dpEGFR_c_Cbl pShc_dpEGFR_c_Cbl_ubiq pTrkA pFRS2_pTrkA_endo dpEGFR_c_Cbl_ubiq pDok_RasGAP Crk_C3G_pFRS2_pTrkA SOS FRS2_dpEGFR_c_Cbl_ubiq Grb2_SOS_pShc_pTrkA_endo Dok L_EGFR_dimer ppMEK_ERK Grb2 pShc_pTrkA_endo C3G B_Raf_Ras_GTP_MEK_ERK Grb2_SOS_pShc Shc_dpEGFR_c_Cbl_ubiq c_Raf
var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error var error
0.0 BioUML0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,000,00000E00,003,00000E-10,000,00000E00,001,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,005,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,006,18940E-20,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,002,60000E-10,000,00000E00,000,00000E00,006,80000E-10,000,00000E00,001,80000E-20,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,003,00000E-10,000,00000E00,000,00000E00,001,00000E00,000,00000E00,005,00000E-10,000,00000E00,000,00000E00,000,00000E00,005,00000E-10,00
0.0 ByoDyn0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,000,00000E00,003,00000E-10,000,00000E00,001,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,005,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,006,18940E-20,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,002,60000E-10,000,00000E00,000,00000E00,006,80000E-10,000,00000E00,001,80000E-20,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,003,00000E-10,000,00000E00,000,00000E00,001,00000E00,000,00000E00,005,00000E-10,000,00000E00,000,00000E00,000,00000E00,005,00000E-10,00
0.0 Jarnac0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,000,00000E00,003,00000E-10,000,00000E00,001,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,005,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,006,18940E-20,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,002,60000E-10,000,00000E00,000,00000E00,006,80000E-10,000,00000E00,001,80000E-20,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,003,00000E-10,000,00000E00,000,00000E00,001,00000E00,000,00000E00,005,00000E-10,000,00000E00,000,00000E00,000,00000E00,005,00000E-10,00
0.0 MathSBML0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,000,00000E00,003,00000E-10,000,00000E00,001,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,005,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,006,18940E-20,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,002,60000E-10,000,00000E00,000,00000E00,006,80000E-10,000,00000E00,001,80000E-20,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,003,00000E-10,000,00000E00,000,00000E00,001,00000E00,000,00000E00,005,00000E-10,000,00000E00,000,00000E00,000,00000E00,005,00000E-10,00
0.0 Oscill8 Core0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,00 - - 2,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,00 - - 0,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,00 - - 3,00000E-10,000,00000E00,00 - - 0,00000E00,000,00000E00,000,00000E00,000,00000E00,005,00000E-10,00 - - 0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,006,18940E-20,000,00000E00,00 - - 0,00000E00,00 - - 0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,00 - - 0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,00 - - 0,00000E00,00 - - 0,00000E00,000,00000E00,001,00000E00,000,00000E00,00 - - 0,00000E00,000,00000E00,002,60000E-10,000,00000E00,000,00000E00,006,80000E-10,00 - - 1,80000E-20,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,00 - - 0,00000E00,00 - - 0,00000E00,000,00000E00,003,00000E-10,000,00000E00,000,00000E00,001,00000E00,000,00000E00,00 - - 0,00000E00,000,00000E00,000,00000E00,00 - -
0.0 SBToolbox20,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,000,00000E00,003,00000E-10,000,00000E00,001,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,005,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,006,18940E-20,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,002,60000E-10,000,00000E00,000,00000E00,006,80000E-10,000,00000E00,001,80000E-20,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,003,00000E-10,000,00000E00,000,00000E00,001,00000E00,000,00000E00,005,00000E-10,000,00000E00,000,00000E00,000,00000E00,005,00000E-10,00
0.0 SBWOdeSolver0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,000,00000E00,003,00000E-10,000,00000E00,001,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,005,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,006,18940E-20,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,002,60000E-10,000,00000E00,000,00000E00,006,80000E-10,000,00000E00,001,80000E-20,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,003,00000E-10,000,00000E00,000,00000E00,001,00000E00,000,00000E00,005,00000E-10,000,00000E00,000,00000E00,000,00000E00,005,00000E-10,00
0.0 VCell0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,000,00000E00,003,00000E-10,000,00000E00,001,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,005,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,006,18940E-20,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,002,60000E-10,000,00000E00,000,00000E00,006,80000E-10,000,00000E00,001,80000E-20,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,003,00000E-10,000,00000E00,000,00000E00,001,00000E00,000,00000E00,005,00000E-10,000,00000E00,000,00000E00,000,00000E00,005,00000E-10,00
0.0 copasi0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,000,00000E00,002,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,000,00000E00,003,00000E-10,000,00000E00,001,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,005,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,006,18940E-20,000,00000E00,000,00000E00,000,00000E00,00-2,12549E-160,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,001,00000E00,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,002,60000E-10,000,00000E00,000,00000E00,006,80000E-10,000,00000E00,001,80000E-20,000,00000E00,001,00000E-10,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,00<