Test: BIOMD0000000067.xml - Ok

test: BIOMD0000000067.xml
model: xml, reaction graph
plots: plot
comparison: comparison of simulators

Reaction graph

Note: downloaded from http://www.ebi.ac.uk/compneur-srv/biomodels/models-main/publ/BIOMD0000000067.gif

Plots

Note: downloaded from http://www.ebi.ac.uk/compneur-srv/biomodels/models-main/simu/MODEL6624231052.JPG

Comparison with other simulators

Legend:

Text color indicates difference between values:
  -  no significant difference ( < 0.1%)
  -  small relative error ( > 0.1% and <50%)
  -  simulation results significantly differ ( >50%)

Variables: Pta  Acs  LacI  AcP  AcCoA  OAc  HOAc 
Simulators: BioUML  ByoDyn  Jarnac  MathSBML  Oscill8 Core  SBToolbox2  SBWOdeSolver  VCell  copasi  edu.kgi.roadRunner  jsim 
timesimulation Pta Acs LacI AcP AcCoA OAc HOAc
var error var error var error var error var error var error var error
0.0 BioUML0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,00
0.0 ByoDyn0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,00
0.0 Jarnac0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,00
0.0 MathSBML0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,00
0.0 Oscill8 Core0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,00
0.0 SBToolbox20,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,00
0.0 SBWOdeSolver0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,00
0.0 VCell0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,00
0.0 copasi0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,00
0.0 edu.kgi.roadRunner0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,00
0.0 jsim0,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,000,00000E00,00
0.2 BioUML3,97610E-10,009,60825E-60,004,80412E-70,008,58692E-20,009,49056E-40,007,75067E-30,004,92504E-90,00
0.2 ByoDyn3,97610E-10,009,60825E-60,004,80412E-70,008,58692E-20,009,49056E-40,007,75067E-30,004,92504E-90,00
0.2 Jarnac3,97610E-10,009,60825E-60,004,80412E-70,008,58692E-20,009,49056E-40,007,75067E-30,004,92504E-90,00
0.2 MathSBML3,97610E-10,009,60833E-60,004,80417E-70,008,58692E-20,009,49056E-40,007,75065E-30,004,92508E-90,00
0.2 Oscill8 Core3,97609E-10,009,60965E-60,004,80483E-70,008,58688E-20,009,49093E-40,007,75099E-30,004,92580E-90,00
0.2 SBToolbox23,97615E-10,009,60808E-60,004,80399E-70,008,58702E-20,009,48848E-40,007,75121E-30,004,92699E-90,00
0.2 SBWOdeSolver3,97609E-10,009,60966E-60,004,80483E-70,008,58689E-20,009,49107E-40,007,75100E-30,004,92581E-90,00
0.2 VCell3,97610E-10,009,60825E-60,004,80412E-70,008,58692E-20,009,49056E-40,007,75067E-30,004,92504E-90,00
0.2 copasi3,97610E-10,009,60828E-60,004,80414E-70,008,58692E-20,009,49056E-40,007,75066E-30,004,92506E-90,00
0.2 edu.kgi.roadRunner3,97610E-10,009,60825E-60,004,80412E-70,008,58692E-20,009,49056E-40,007,75067E-30,004,92504E-90,00
0.2 jsim3,97610E-10,009,60825E-60,004,80412E-70,008,58692E-20,009,49072E-40,007,75067E-30,004,92504E-90,00
0.4 BioUML7,90475E-10,007,42382E-50,003,71191E-60,001,63440E-10,004,74750E-40,002,93396E-20,003,99284E-80,00
0.4 ByoDyn7,90475E-10,007,42382E-50,003,71191E-60,001,63440E-10,004,74750E-40,002,93396E-20,003,99284E-80,00
0.4 Jarnac7,90475E-10,007,42382E-50,003,71191E-60,001,63440E-10,004,74750E-40,002,93396E-20,003,99284E-80,00
0.4 MathSBML7,90475E-10,007,42385E-50,003,71193E-60,001,63440E-10,004,74750E-40,002,93395E-20,003,99285E-80,00
0.4 Oscill8 Core7,90474E-10,007,42425E-50,003,71213E-60,001,63440E-10,004,74772E-40,002,93400E-20,003,99308E-80,00
0.4 SBToolbox27,90479E-10,007,42344E-50,003,71172E-60,001,63445E-10,004,74621E-40,002,93398E-20,003,99360E-80,00
0.4 SBWOdeSolver7,90474E-10,007,42427E-50,003,71214E-60,001,63440E-10,004,74761E-40,002,93400E-20,003,99309E-80,00
0.4 VCell7,90475E-10,007,42382E-50,003,71191E-60,001,63440E-10,004,74750E-40,002,93396E-20,003,99284E-80,00
0.4 copasi7,90475E-10,007,42383E-50,003,71192E-60,001,63440E-10,004,74750E-40,002,93396E-20,003,99284E-80,00
0.4 edu.kgi.roadRunner7,90475E-10,007,42382E-50,003,71191E-60,001,63440E-10,004,74750E-40,002,93396E-20,003,99284E-80,00
0.4 jsim7,90475E-10,007,42382E-50,003,71191E-60,001,63440E-10,004,74764E-40,002,93396E-20,003,99284E-80,00
0.6 BioUML1,17863E00,002,31345E-40,001,15673E-50,002,31992E-10,003,18195E-40,006,01717E-20,001,27245E-70,00
0.6 ByoDyn1,17863E00,002,31345E-40,001,15673E-50,002,31992E-10,003,18195E-40,006,01717E-20,001,27245E-70,00
0.6 Jarnac1,17863E00,002,31345E-40,001,15673E-50,002,31992E-10,003,18195E-40,006,01717E-20,001,27245E-70,00
0.6 MathSBML1,17863E00,002,31346E-40,001,15673E-50,002,31992E-10,003,18195E-40,006,01717E-20,001,27245E-70,00
0.6 Oscill8 Core1,17863E00,002,31353E-40,001,15677E-50,002,31992E-10,003,18197E-40,006,01722E-20,001,27250E-70,00
0.6 SBToolbox21,17864E00,002,31321E-40,001,15665E-50,002,31995E-10,003,18095E-40,006,01714E-20,001,27258E-70,00
0.6 SBWOdeSolver1,17863E00,002,31353E-40,001,15677E-50,002,31992E-10,003,18199E-40,006,01722E-20,001,27250E-70,00
0.6 VCell1,17863E00,002,31345E-40,001,15673E-50,002,31992E-10,003,18195E-40,006,01717E-20,001,27245E-70,00
0.6 copasi1,17863E00,002,31345E-40,001,15673E-50,002,31992E-10,003,18195E-40,006,01717E-20,001,27245E-70,00
0.6 edu.kgi.roadRunner1,17863E00,002,31345E-40,001,15673E-50,002,31992E-10,003,18195E-40,006,01717E-20,001,27245E-70,00
0.6 jsim1,17863E00,002,31345E-40,001,15673E-50,002,31992E-10,003,18219E-40,006,01717E-20,001,27245E-70,00
0.8 BioUML1,56205E00,005,06181E-40,002,53091E-50,002,94472E-10,002,40110E-40,009,72198E-20,002,81416E-70,00
0.8 ByoDyn1,56205E00,005,06181E-40,002,53091E-50,002,94472E-10,002,40110E-40,009,72198E-20,002,81416E-70,00
0.8 Jarnac1,56205E00,005,06181E-40,002,53091E-50,002,94472E-10,002,40110E-40,009,72198E-20,002,81416E-70,00
0.8 MathSBML1,56205E00,005,06182E-40,002,53091E-50,002,94472E-10,002,40109E-40,009,72197E-20,002,81416E-70,00
0.8 Oscill8 Core1,56205E00,005,06193E-40,002,53097E-50,002,94471E-10,002,40113E-40,009,72202E-20,002,81423E-70,00
0.8 SBToolbox21,56207E00,005,06119E-40,002,53055E-50,002,94479E-10,002,39976E-40,009,72177E-20,002,81442E-70,00
0.8 SBWOdeSolver1,56205E00,005,06194E-40,002,53097E-50,002,94471E-10,002,40112E-40,009,72202E-20,002,81423E-70,00
0.8 VCell1,56205E00,005,06181E-40,002,53091E-50,002,94472E-10,002,40110E-40,009,72198E-20,002,81416E-70,00
0.8 copasi1,56205E00,005,06181E-40,002,53091E-50,002,94472E-10,002,40110E-40,009,72198E-20,002,81416E-70,00
0.8 edu.kgi.roadRunner1,56205E00,005,06181E-40,002,53091E-50,002,94472E-10,002,40110E-40,009,72198E-20,002,81416E-70,00
0.8 jsim1,56205E00,005,06181E-40,002,53091E-50,002,94472E-10,002,40161E-40,009,72198E-20,002,81416E-70,00
1.0 BioUML1,94053E00,009,18234E-40,004,59117E-50,003,52869E-10,001,93357E-40,001,38438E-10,005,11831E-70,00
1.0 ByoDyn1,94053E00,009,18234E-40,004,59117E-50,003,52869E-10,001,93357E-40,001,38438E-10,005,11831E-70,00
1.0 Jarnac1,94053E00,009,18234E-40,004,59117E-50,003,52869E-10,001,93357E-40,001,38438E-10,005,11831E-70,00
1.0 MathSBML1,94053E00,009,18236E-40,004,59118E-50,003,52869E-10,001,93357E-40,001,38438E-10,005,11831E-70,00
1.0 Oscill8 Core1,94052E00,009,18251E-40,004,59125E-50,003,52869E-10,001,93368E-40,001,38439E-10,005,11840E-70,00
1.0 SBToolbox21,94052E00,009,18093E-40,004,59051E-50,003,52875E-10,001,93236E-40,001,38436E-10,005,11864E-70,00
1.0 SBWOdeSolver1,94052E00,009,18252E-40,004,59126E-50,003,52869E-10,001,93359E-40,001,38439E-10,005,11840E-70,00
1.0 VCell1,94053E00,009,18234E-40,004,59117E-50,003,52869E-10,001,93357E-40,001,38438E-10,005,11831E-70,00
1.0 copasi1,94053E00,009,18234E-40,004,59117E-50,003,52869E-10,001,93357E-40,001,38438E-10,005,11831E-70,00
1.0 edu.kgi.roadRunner1,94053E00,009,18234E-40,004,59117E-50,003,52869E-10,001,93357E-40,001,38438E-10,005,11831E-70,00
1.0 jsim1,94053E00,009,18234E-40,004,59117E-50,003,52869E-10,001,93406E-40,001,38438E-10,005,11831E-70,00
1.2 BioUML2,31356E00,001,48446E-30,007,42232E-50,004,08538E-10,001,62290E-40,001,82447E-10,008,24407E-70,00
1.2 ByoDyn2,31356E00,001,48446E-30,007,42232E-50,004,08538E-10,001,62290E-40,001,82447E-10,008,24407E-70,00
1.2 Jarnac2,31356E00,001,48446E-30,007,42232E-50,004,08538E-10,001,62290E-40,001,82447E-10,008,24407E-70,00
1.2 MathSBML2,31356E00,001,48447E-30,007,42233E-50,004,08538E-10,001,62290E-40,001,82447E-10,008,24408E-70,00
1.2 Oscill8 Core2,31356E00,001,48449E-30,007,42243E-50,004,08537E-10,001,62284E-40,001,82448E-10,008,24418E-70,00
1.2 SBToolbox22,31358E00,001,48422E-30,007,42102E-50,004,08542E-10,001,62184E-40,001,82440E-10,008,24448E-70,00
1.2 SBWOdeSolver2,31356E00,001,48449E-30,007,42243E-50,004,08537E-10,001,62291E-40,001,82448E-10,008,24418E-70,00
1.2 VCell2,31356E00,001,48446E-30,007,42232E-50,004,08538E-10,001,62290E-40,001,82447E-10,008,24407E-70,00
1.2 copasi2,31356E00,001,48446E-30,007,42232E-50,004,08538E-10,001,62290E-40,001,82447E-10,008,24407E-70,00
1.2 edu.kgi.roadRunner2,31356E00,001,48446E-30,007,42232E-50,004,08538E-10,001,62290E-40,001,82447E-10,008,24407E-70,00
1.2 jsim2,31356E00,001,48446E-30,007,42232E-50,004,08538E-10,001,62341E-40,001,82447E-10,008,24407E-70,00
1.4 BioUML2,68020E00,002,22087E-30,001,11043E-40,004,62390E-10,001,40222E-40,002,28315E-10,001,22272E-60,00
1.4 ByoDyn2,68020E00,002,22087E-30,001,11043E-40,004,62390E-10,001,40221E-40,002,28315E-10,001,22272E-60,00
1.4 Jarnac2,68020E00,002,22087E-30,001,11043E-40,004,62390E-10,001,40222E-40,002,28315E-10,001,22272E-60,00
1.4 MathSBML2,68020E00,002,22087E-30,001,11043E-40,004,62390E-10,001,40225E-40,002,28315E-10,001,22272E-60,00
1.4 Oscill8 Core2,68020E00,002,22090E-30,001,11045E-40,004,62390E-10,001,40222E-40,002,28315E-10,001,22274E-60,00
1.4 SBToolbox22,68025E00,002,22043E-30,001,11022E-40,004,62398E-10,001,40114E-40,002,28314E-10,001,22281E-60,00
1.4 SBWOdeSolver2,68020E00,002,22090E-30,001,11045E-40,004,62390E-10,001,40222E-40,002,28315E-10,001,22274E-60,00
1.4 VCell2,68020E00,002,22087E-30,001,11043E-40,004,62390E-10,001,40222E-40,002,28315E-10,001,22272E-60,00
1.4 copasi2,68020E00,002,22087E-30,001,11043E-40,004,62390E-10,001,40222E-40,002,28315E-10,001,22272E-60,00
1.4 edu.kgi.roadRunner2,68020E00,002,22087E-30,001,11043E-40,004,62390E-10,001,40222E-40,002,28315E-10,001,22272E-60,00
1.4 jsim2,68020E00,002,22087E-30,001,11043E-40,004,62390E-10,001,40248E-40,002,28315E-10,001,22272E-60,00
1.6 BioUML3,03883E00,003,14320E-30,001,57160E-40,005,15046E-10,001,23825E-40,002,75412E-10,001,70879E-60,00
1.6 ByoDyn3,03883E00,003,14320E-30,001,57160E-40,005,15046E-10,001,23825E-40,002,75412E-10,001,70879E-60,00
1.6 Jarnac3,03883E00,003,14320E-30,001,57160E-40,005,15046E-10,001,23825E-40,002,75412E-10,001,70879E-60,00
1.6 MathSBML3,03883E00,003,14321E-30,001,57160E-40,005,15046E-10,001,23825E-40,002,75412E-10,001,70879E-60,00
1.6 Oscill8 Core3,03883E00,003,14324E-30,001,57162E-40,005,15046E-10,001,23835E-40,002,75412E-10,001,70880E-60,00
1.6 SBToolbox23,03887E00,003,14246E-30,001,57124E-40,005,15052E-10,001,23727E-40,002,75409E-10,001,70886E-60,00
1.6 SBWOdeSolver3,03883E00,003,14325E-30,001,57162E-40,005,15046E-10,001,23826E-40,002,75412E-10,001,70880E-60,00
1.6 VCell3,03883E00,003,14320E-30,001,57160E-40,005,15046E-10,001,23825E-40,002,75412E-10,001,70879E-60,00
1.6 copasi3,03883E00,003,14320E-30,001,57160E-40,005,15046E-10,001,23825E-40,002,75412E-10,001,70879E-60,00
1.6 edu.kgi.roadRunner3,03883E00,003,14320E-30,001,57160E-40,005,15046E-10,001,23825E-40,002,75412E-10,001,70879E-60,00
1.6 jsim3,03883E00,003,14320E-30,001,57160E-40,005,15046E-10,001,23941E-40,002,75412E-10,001,70879E-60,00
1.8 BioUML3,38703E00,004,26729E-30,002,13365E-40,005,66921E-10,001,11266E-40,003,23314E-10,002,28354E-60,00
1.8 ByoDyn3,38703E00,004,26729E-30,002,13365E-40,005,66921E-10,001,11266E-40,003,23314E-10,002,28354E-60,00
1.8 Jarnac3,38703E00,004,26729E-30,002,13365E-40,005,66921E-10,001,11266E-40,003,23314E-10,002,28354E-60,00
1.8 MathSBML3,38703E00,004,26729E-30,002,13365E-40,005,66921E-10,001,11266E-40,003,23314E-10,002,28354E-60,00
1.8 Oscill8 Core3,38702E00,004,26733E-30,002,13366E-40,005,66921E-10,001,11270E-40,003,23314E-10,002,28356E-60,00
1.8 SBToolbox23,38702E00,004,26625E-30,002,13317E-40,005,66934E-10,001,11167E-40,003,23306E-10,002,28354E-60,00
1.8 SBWOdeSolver3,38702E00,004,26734E-30,002,13367E-40,005,66921E-10,001,11266E-40,003,23314E-10,002,28356E-60,00
1.8 VCell3,38703E00,004,26729E-30,002,13365E-40,005,66921E-10,001,11266E-40,003,23314E-10,002,28354E-60,00
1.8 copasi3,38703E00,004,26729E-30,002,13365E-40,005,66921E-10,001,11266E-40,003,23314E-10,002,28354E-60,00
1.8 edu.kgi.roadRunner3,38703E00,004,26729E-30,002,13365E-40,005,66921E-10,001,11266E-40,003,23314E-10,002,28354E-60,00
1.8 jsim3,38703E00,004,26729E-30,002,13365E-40,005,66921E-10,001,11287E-40,003,23314E-10,002,28354E-60,00
2.0 BioUML3,72144E00,005,60910E-30,002,80455E-40,006,18300E-10,001,01456E-40,003,71733E-10,002,94722E-60,00
2.0 ByoDyn3,72144E00,005,60910E-30,002,80455E-40,006,18300E-10,001,01456E-40,003,71733E-10,002,94722E-60,00
2.0 Jarnac3,72144E00,005,60910E-30,002,80455E-40,006,18300E-10,001,01456E-40,003,71733E-10,002,94722E-60,00
2.0 MathSBML3,72144E00,005,60911E-30,002,80455E-40,006,18300E-10,001,01456E-40,003,71733E-10,002,94722E-60,00
2.0 Oscill8 Core3,72143E00,005,60915E-30,002,80457E-40,006,18299E-10,001,01456E-40,003,71733E-10,002,94724E-60,00
2.0 SBToolbox23,72154E00,005,60746E-30,002,80374E-40,006,18308E-10,001,01358E-40,003,71724E-10,002,94722E-60,00
2.0 SBWOdeSolver3,72143E00,005,60916E-30,002,80458E-40,006,18300E-10,001,01456E-40,003,71732E-10,002,94724E-60,00
2.0 VCell3,72144E00,005,60910E-30,002,80455E-40,006,18300E-10,001,01456E-40,003,71733E-10,002,94722E-60,00
2.0 copasi3,72144E00,005,60910E-30,002,80455E-40,006,18300E-10,001,01456E-40,003,71733E-10,002,94722E-60,00
2.0 edu.kgi.roadRunner3,72144E00,005,60910E-30,002,80455E-40,006,18300E-10,001,01456E-40,003,71733E-10,002,94722E-60,00
2.0 jsim3,72144E00,005,60910E-30,002,80455E-40,006,18300E-10,001,01475E-40,003,71733E-10,002,94722E-60,00
2.2 BioUML4,03784E00,007,18478E-30,003,59239E-40,006,69373E-10,009,37123E-50,004,20472E-10,003,69959E-60,00
2.2 ByoDyn4,03784E00,007,18478E-30,003,59239E-40,006,69373E-10,009,37124E-50,004,20472E-10,003,69959E-60,00
2.2 Jarnac4,03784E00,007,18478E-30,003,59239E-40,006,69373E-10,009,37123E-50,004,20472E-10,003,69959E-60,00
2.2 MathSBML4,03784E00,007,18478E-30,003,59239E-40,006,69373E-10,009,37119E-50,004,20472E-10,003,69959E-60,00
2.2 Oscill8 Core4,03784E00,007,18484E-30,003,59242E-40,006,69373E-10,009,37136E-50,004,20472E-10,003,69961E-60,00
2.2 SBToolbox24,03803E00,007,18244E-30,003,59117E-40,006,69379E-10,009,35892E-50,134,20463E-10,003,69954E-60,00
2.2 SBWOdeSolver4,03783E00,007,18485E-30,003,59243E-40,006,69373E-10,009,37128E-50,004,20472E-10,003,69961E-60,00
2.2 VCell4,03784E00,007,18478E-30,003,59239E-40,006,69373E-10,009,37123E-50,004,20472E-10,003,69959E-60,00
2.2 copasi4,03784E00,007,18478E-30,003,59239E-40,006,69373E-10,009,37124E-50,004,20472E-10,003,69959E-60,00
2.2 edu.kgi.roadRunner4,03784E00,007,18478E-30,003,59239E-40,006,69373E-10,009,37123E-50,004,20472E-10,003,69959E-60,00
2.2 jsim4,03784E00,007,18478E-30,003,59239E-40,006,69373E-10,009,37610E-50,004,20472E-10,003,69959E-60,00
2.4 BioUML4,33143E00,009,01060E-30,004,50530E-40,007,20271E-10,008,75861E-50,004,69397E-10,004,54009E-60,00
2.4 ByoDyn4,33143E00,009,01060E-30,004,50530E-40,007,20271E-10,008,75861E-50,004,69397E-10,004,54009E-60,00
2.4 Jarnac4,33143E00,009,01060E-30,004,50530E-40,007,20271E-10,008,75861E-50,004,69397E-10,004,54009E-60,00
2.4 MathSBML4,33143E00,009,01060E-30,004,50530E-40,007,20271E-10,008,75983E-50,004,69397E-10,004,54009E-60,00
2.4 Oscill8 Core4,33143E00,009,01066E-30,004,50533E-40,007,20271E-10,008,75862E-50,004,69397E-10,004,54011E-60,00
2.4 SBToolbox24,33164E00,009,00725E-30,004,50359E-40,007,20280E-10,008,74665E-50,144,69392E-10,004,54009E-60,00
2.4 SBWOdeSolver4,33142E00,009,01068E-30,004,50534E-40,007,20271E-10,008,75866E-50,004,69397E-10,004,54011E-60,00
2.4 VCell4,33143E00,009,01060E-30,004,50530E-40,007,20271E-10,008,75861E-50,004,69397E-10,004,54009E-60,00
2.4 copasi4,33143E00,009,01060E-30,004,50530E-40,007,20271E-10,008,75861E-50,004,69397E-10,004,54009E-60,00
2.4 edu.kgi.roadRunner4,33143E00,009,01060E-30,004,50530E-40,007,20271E-10,008,75861E-50,004,69397E-10,004,54009E-60,00
2.4 jsim4,33143E00,009,01060E-30,004,50530E-40,007,20271E-10,008,76387E-50,004,69397E-10,004,54009E-60,00
2.6 BioUML4,59735E00,001,11029E-20,005,55145E-40,007,71085E-10,008,27659E-50,005,18417E-10,005,46793E-60,00
2.6 ByoDyn4,59735E00,001,11029E-20,005,55145E-40,007,71085E-10,008,27659E-50,005,18417E-10,005,46793E-60,00
2.6 Jarnac4,59735E00,001,11029E-20,005,55145E-40,007,71085E-10,008,27659E-50,005,18417E-10,005,46793E-60,00
2.6 MathSBML4,59735E00,001,11029E-20,005,55145E-40,007,71085E-10,008,27659E-50,005,18417E-10,005,46793E-60,00
2.6 Oscill8 Core4,59734E00,001,11030E-20,005,55148E-40,00